Personalized digital care for depression 

Thrive is a digital program for depression that distills best practices from cognitive behavior therapy (CBT) and teaches them to individuals them through a rich, structured and guided digital curriculum. In both trial and real-world settings, Thrive enrollees have shown high engagement rates and experienced substantial depression symptom improvements.

Fully automated and simple to deploy, Thrive is ideally suited to help healthcare organizations cost-effectively augment existing behavioral health resources to extend care to their high-cost members. And because it’s fully cloud-based, no IT integration is required.


Thrive desktop and mobile combo



Thrive has produced excellent adherence and depression symptom reductions with no telephone or face-to-face support. Among commercially insured individuals:

  • 86% of individuals requesting access to Thrive go on to enroll
  • 6+ logins per enrollee
  • 42% PHQ-9 reduction over 6-7 weeks among enrollees with baseline PHQ-9 score ≥5

The Thrive curriculum

Thrive uses a combination of symptom assessments, video, interactive tools and branching logic to create a personalized yet structured curriculum for each patient. When patients log in, Thrive remembers what they’ve completed, what they’ve said about how depression is affecting them, and what they’re working on. As Thrive learns more about patients, it offers increasingly specific feedback and recommendations.

Thrive includes three CBT modules based on behavioral activation, cognitive restructuring, and social skills training techniques. Each module is comprised of ten lessons.

Thrive also features the Patient Health Questionnaire – 9 (PHQ-9), allowing users and clinicians to track progress.

By combining the efficacy of CBT, the consistency of software, and the availability of the Internet, Thrive enables care for depression that is effective, standardized, measurable, and scalable.



Clinicians and Thrive

Thrive is designed to support clinicians and case managers as they care for patients with depression. The Coach’s Portal allows authorized personnel to view patients’ assessments scores and use of Thrive, providing the foundation for progress reviews with patients.


Earlier versions of Thrive were shown to be effective in clinical trial. Please see:

  • Whiteside U, Richards J, Steinfeld B, Simon G, Caka S, Tachibana C, Stuckey S, Ludman E. Online cognitive behavioral therapy for depressed primary care patients: a pilot feasibility project. The Permanente Journal. 2014 Spring;18(2):21-27.
  • Marks IM, Mataix-Cols D, Kenwright M, Cameron R, Hirsch S, Gega L. Pragmatic evaluation of computer-aided self-help for anxiety and depression. Br J Psychiatry. 2003 Jul;183:57-65. PubMed PMID: 12835245.
  • Osgood-Hynes DJ, Greist JH, Marks IM, Baer L, Heneman SW, Wenzel KW, Manzo PA, Parkin JR, Spierings CJ, Dottl SL, Vitse HM. Self-administered psychotherapy for depression using a telephone-accessed computer system plus booklets: an open U.S.-U.K. study. J Clin Psychiatry. 1998 Jul;59(7):358-65.

To discuss how Thrive can help your healthcare organization provide a more effective, cost-efficient, and measurable depression management solution, please contact us.